Weapons
Unlike Super Metroid, Metroid Prime does not allow the player to combine separate beams into one, due to the fact that each of the four main beams has a unique use. Also, each beam has a Charge Combo that can be acquired that utilizes Missiles to perform a more powerful attack.
Charge Beam
The charge beam is an add-on for all of Samus' primary beams; holding down the A button causes Samus to build up energy which is fired when the button is released, creating a much more powerful attack than would normally result. It also allows access to the various Charge Combos.
Power Beam
This is the default beam that Samus begins the game with. It has the highest rate of fire of all the beams. While notably weaker than any other weapon, it is the only beam which can damage certain enemies. Its Charge Combo, Super Missiles, fires more powerful Missiles.
Wave Beam
This beam fires three blasts of electricity that can home in on enemies to a certain extent. Its charged shot usually stuns stronger enemies for a short period of time. It can also re-energize power conduits (required to open many doors) and open purple doors. Its Charge Combo, Wave Buster, automatically locks on to enemies but requires the largest number of Missiles to activate and continue using.
Ice Beam
This beam fires slow-moving blasts of ice that can freeze enemies. Its individual blasts are notably more powerful than the Wave Beam's, but its slow rate of fire makes it somewhat unwieldy. Frozen enemies can be shattered with a single Missile. It also opens white doors. The Ice Beam's Charge Combo, the Ice Spreader, spreads ice over a wide area where it hits and is somewhat limited against aerial and fast targets.
Plasma Beam
This is the most powerful beam in terms of raw offensive power. It fires blasts of intense heat, which either kill instantly or set enemies aflame until they die. It cannot home in on targets and it has a short range. It can also open red doors and melt thick ice. Its Charge Combo, Flamethrower, shoots a stream of flame.
Phazon Beam
This beam can only be used during the final boss battle. Samus receives this item along with the Phazon Suit.
Missiles
A Metroid series mainstay, Missiles fire homing concussive blasts that cause more damage than most beam attacks. Missiles can break certain door locks and other obstacles. Each Missile expansion increases Samus' missile holding capacity by five.